A cosmetic doctor examining female patient skin to treat saggy skin and wrinkles

Types of Collagen Bio-Stimulators

1. Collagen Stimulator E
(70% Volume 30% Collagen Stimulation)

The injection is made of polycaprolactone (PCL) microspheres which are suspended in a water-based carboxymethylcellulose (CMC) gel–carrier. Once injected, there are immediate visible results which remain throughout the chosen period of longevity.


2. Collagen Stimulator S
(30% Volume 70% Collagen Stimulation)

The injection is made of a synthetic substance called poly-L-lactic acid (PLLA), which is biocompatible and biodegradable. The effects of Sculptra are gradual, with optimal results typically seen after two to three treatment sessions spaced several weeks apart.


Natural-looking, youthful appearance

Stimulates natural collagen production

Improve skin texture, tone, and firmness

Address a range of skin concerns

Restore lost volume, reducing the appearance of wrinkles and fine lines

Minimal side effects

Safe and effective treatment option, with a low risk of adverse reactions and side effects

Minimal downtime

Minimally invasive treatment

Key Information

The signs of skin ageing usually begin to appear in your 20’s as your levels of collagen and elastin begin to deplete. Collagen and elastin are structural proteins found throughout the body. In the skin, collagen provides the infrastructure for elastin and hyaluronic acid to bind to and gives skin a firm and full appearance.

Elastin is an extracellular matrix protein that gives skin elasticity, and hyaluronic acid binds to water, keeping the skin moist and plump. With age, collagen levels naturally deplete leading to a disorganised collagen network and decreased elastin and hyaluronic acid. 

Collagen stimulators like Sculptra and Ellanse have become popular in recent years because they offer a longer-lasting solution to treating wrinkles, fine lines, and volume loss compared to traditional Dermal fillers. They work by stimulating the body's natural collagen production, resulting in a gradual and natural-looking improvement in skin texture, elasticity, and volume over time. Additionally, collagen stimulators are biocompatible and biodegradable, meaning they are well-tolerated by the body and do not require allergy testing before treatment.


Sculptra and Ellanse are both Collagen Stimulators used for facial rejuvenation, but they have some differences. Sculptra is made of Poly-L-lactic acid, while Ellanse is composed of Polycaprolactone Microspheres suspended in a Carboxymethylcellulose gel.


The main difference between Sculptra and Ellanse is the duration of their effects. Sculptra typically lasts for up to two years, while Ellanse can last for up to one, two years or longer depending on the type of Ellanse used. Additionally, Sculptra requires a series of treatments over several months, while Ellanse can provide more immediate results with fewer treatments. Finally, Sculptra stimulates collagen production over time, while Ellanse's microspheres provide immediate volume and gradually stimulate collagen production as they are broken down by the body.


Collagen Stimulators can increase volume and decrease wrinkles and fine lines, but they work differently from regular Dermal Fillers. They boost the body's natural collagen production, which can result in gradual and natural improvements over time. However, they may not work well for all facial areas and may require multiple sessions to achieve desired results. Thus, they may not replace dermal fillers but can be combined with them for a more complete treatment plan. It's best to consult with a qualified practitioner like Dr Tina to determine the best approach for individual needs and preferences.


Determining whether Collagen Stimulator is the appropriate treatment for you depends on a variety of factors, including your specific cosmetic goals, the areas of the face you wish to address, and your medical history. The best way to determine which treatment is right for you is to consult with a qualified medical professional such as Dr Tina, who can evaluate your unique situation and provide personalized recommendations. Dr Tina can also explain the potential risks and benefits of each treatment, so you can make an informed decision.


Like any medical treatment Collagen Stimulator treatments carry some risks and potential side effects. Common side effects may include swelling, bruising, redness, tenderness, and itching at the injection site, which are usually temporary and resolve on their own within a few days or weeks. In rare cases, more severe side effects such as infection, granulomas, and skin necrosis may occur.


A middle aged woman receiving advice from cosmetic doctor on treating wrinkles at clinic

Aftercare Instructions for Collagen Bio-Stimulator

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